Rubia Casagrande Selected Research

phenylbenzoquinone

12/2022	Pimenta pseudocaryophyllus (Gomes) Landrum extract inhibits inflammatory pain in mice: targeting neutrophil recruitment, oxidative stress, and cytokine production.
7/2017	Probucol attenuates overt pain-like behavior and carrageenan-induced inflammatory hyperalgesia and leukocyte recruitment by inhibiting NF-кB activation and cytokine production without antioxidant effects.
1/2016	Antinociceptive Effect of Tephrosia sinapou Extract in the Acetic Acid, Phenyl-p-benzoquinone, Formalin, and Complete Freund's Adjuvant Models of Overt Pain-Like Behavior in Mice.
8/2015	Vanillic Acid Inhibits Inflammatory Pain by Inhibiting Neutrophil Recruitment, Oxidative Stress, Cytokine Production, and NFκB Activation in Mice.
2/2015	Protective effects of the flavonoid hesperidin methyl chalcone in inflammation and pain in mice: role of TRPV1, oxidative stress, cytokines and NF-κB.
1/2015	Vinpocetine reduces carrageenan-induced inflammatory hyperalgesia in mice by inhibiting oxidative stress, cytokine production and NF-κB activation in the paw and spinal cord.
6/2013	Vitexin inhibits inflammatory pain in mice by targeting TRPV1, oxidative stress, and cytokines.
4/2013	Analgesic activity of piracetam: effect on cytokine production and oxidative stress.
5/2012	Acetic acid- and phenyl-p-benzoquinone-induced overt pain-like behavior depends on spinal activation of MAP kinases, PI(3)K and microglia in mice.

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Rubia Casagrande Research Topics

Disease

51	Hyperalgesia 12/2022 - 05/2012
50	Pain (Aches) 12/2022 - 11/2009
47	Inflammation (Inflammations) 08/2021 - 01/2013
31	Edema (Dropsy) 08/2021 - 02/2013
13	Arthritis (Polyarthritis) 08/2020 - 05/2017
8	Gout 01/2022 - 05/2017
4	Peritonitis 01/2022 - 04/2015
4	Sunburn 08/2021 - 01/2018
4	Infections 06/2021 - 01/2018
4	Necrosis 12/2020 - 01/2013
4	Neuralgia (Stump Neuralgia) 01/2020 - 01/2016
3	Gouty Arthritis 01/2022 - 01/2018
3	Hypersensitivity (Allergy) 08/2020 - 01/2018
3	Bone Resorption 12/2018 - 12/2013
3	Myalgia 01/2016 - 04/2014
3	Neoplasms (Cancer) 02/2015 - 01/2013
2	Colitis 01/2021 - 02/2013
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2021 - 02/2013
2	Osteoarthritis 12/2020 - 01/2018
2	Chronic Pain 05/2019 - 02/2015

Drug/Important Bio-Agent (IBA)

53	CytokinesIBA 12/2022 - 11/2009
29	Analgesics (Analgesic Drugs)IBA 01/2022 - 11/2009
19	CarrageenanIBA 12/2022 - 05/2012
19	Peroxidase (Myeloperoxidase)IBA 09/2021 - 04/2013
17	Superoxides (Superoxide)IBA 06/2021 - 04/2015
17	AntioxidantsIBA 03/2021 - 02/2013
13	Acetic Acid (Vinegar)FDA LinkGeneric 01/2021 - 05/2012
12	FlavonoidsIBA 01/2021 - 10/2013
11	Formaldehyde (Formol)FDA Link 12/2022 - 04/2013
10	Freund's AdjuvantIBA 12/2022 - 04/2013
9	phenylbenzoquinoneIBA 12/2022 - 05/2012
9	QuercetinIBA 12/2019 - 11/2009
9	Messenger RNA (mRNA)IBA 05/2019 - 01/2016
8	Chalcone (Benzalacetophenone)IBA 01/2021 - 02/2015
7	LipopolysaccharidesIBA 01/2022 - 08/2013
7	Uric Acid (Urate)IBA 01/2022 - 05/2017
7	Etanercept (Enbrel)FDA Link 09/2021 - 04/2014
6	LipidsIBA 01/2022 - 01/2018
6	CollagenIBA 08/2021 - 01/2018
6	naringeninIBA 12/2019 - 07/2015
6	Matrix Metalloproteinase 9 (Gelatinase B)IBA 01/2019 - 07/2015
6	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2019 - 08/2013
6	KATP ChannelsIBA 08/2017 - 05/2012
5	Capsaicin (Zostrix)FDA Link 01/2022 - 04/2013
5	prolinedithiocarbamate (PDTC)IBA 09/2021 - 09/2015
5	HesperidinIBA 01/2021 - 02/2015
5	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 11/2009
5	Interleukin-33IBA 01/2021 - 02/2013
5	Glutathione (Reduced Glutathione)IBA 01/2021 - 07/2014
5	InflammasomesIBA 12/2019 - 05/2017
4	ZymosanIBA 01/2022 - 06/2018
4	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 09/2021 - 07/2014
4	2,2'- azino- di- (3- ethylbenzothiazoline)- 6- sulfonic acid (ABTS)IBA 06/2021 - 04/2016
4	CatalaseIBA 01/2021 - 04/2016
4	Opioid Analgesics (Opioids)IBA 01/2020 - 01/2013
4	vinpocetineIBA 01/2019 - 01/2015
4	Proteoglycans (Proteoglycan)IBA 12/2018 - 01/2017
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 06/2017 - 08/2013
4	Interleukin-10 (Interleukin 10)IBA 01/2017 - 02/2015
4	oxyhyponitriteIBA 01/2017 - 08/2013
4	nitroxylIBA 01/2017 - 08/2013
3	AntigensIBA 01/2022 - 12/2017
3	kaurenoic acidIBA 01/2022 - 05/2012
3	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 09/2021 - 02/2015
3	pyrrolidine dithiocarbamic acidIBA 09/2021 - 06/2016
3	InterleukinsIBA 12/2020 - 07/2014
3	Pharmaceutical PreparationsIBA 06/2020 - 11/2015
3	Probucol (Lorelco)FDA Link 08/2019 - 07/2017
3	Acetaminophen (Paracetamol)FDA LinkGeneric 03/2019 - 01/2013
3	Nootropic Agents (Nootropics)IBA 01/2019 - 04/2013
3	Adenosine Triphosphate (ATP)IBA 01/2019 - 08/2013
3	potassium superoxideIBA 01/2019 - 09/2015
3	budlein AIBA 01/2018 - 12/2017
3	SesquiterpenesIBA 01/2018 - 12/2017
3	LactonesIBA 01/2018 - 12/2017
3	NADPH Oxidases (NAD(P)H oxidase)IBA 07/2017 - 09/2015
3	Naloxone (Narcan)FDA LinkGeneric 05/2017 - 01/2013
3	Cyclic GMPIBA 01/2016 - 05/2012
3	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 09/2015 - 04/2014
3	Type I Tumor Necrosis Factor ReceptorsIBA 09/2015 - 04/2014
3	Morphine (MS Contin)FDA LinkGeneric 02/2015 - 01/2013
3	Cyclic GMP-Dependent Protein Kinases (Protein Kinase G)IBA 11/2014 - 05/2012
2	Sunscreening Agents (Sunscreens)IBA 08/2021 - 10/2016
2	Interleukin-6 (Interleukin 6)IBA 08/2021 - 01/2021
2	Bothrops jararaca VenomIBA 05/2021 - 09/2015
2	Matrix Metalloproteinases (MMPs)IBA 03/2021 - 06/2017
2	Coloring Agents (Dyes)IBA 12/2020 - 04/2015
2	BetalainsIBA 12/2020 - 04/2015
2	Diosmin (Daflon)IBA 01/2020 - 08/2017
2	ChemokinesIBA 01/2020 - 05/2019
2	Biological ProductsIBA 01/2020 - 10/2016
2	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 12/2019 - 02/2015
2	Type II Tumor Necrosis Factor ReceptorsIBA 05/2019 - 09/2015
2	7,14- dihydroxydocosa- 4,8,10,12,16,19- hexaenoic acidIBA 01/2019 - 01/2019
2	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 01/2019 - 09/2018
2	bis(bipyridyl)ruthenium(II)IBA 01/2019 - 04/2013
2	Transcription Factors (Transcription Factor)IBA 01/2019 - 09/2015

Therapy/Procedure

5	Therapeutics 01/2022 - 02/2015
3	Traditional Medicine (Folk Remedies) 01/2022 - 01/2016
3	Analgesia 12/2019 - 08/2014